GDF5 lends a hand to finger abnormalities

In a study appearing online on August 25 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Petra Seemann and colleagues describe two mutations in Growth and Differentiation Factor 5 (GDF5), a signaling molecule, that result in altered binding affinities to the BMP type 1 receptors giving rise to opposing phenotypes, brachydactyly type A2 (unusually short digits) and symphalangism (fusion of the hand joints)... click link for more info. more...

Cosmetic Surgery For Less
Originally Posted on 28/08/2005 07:11:02Content source: http://www.medicalnewstoday.com/medicalnews.php?newsid=29745&nfid=rssfeeds